Search Results for: dg11

Calprotectin Goes Mobile

Big Changes Coming Soon to a Clinic Near You

Calprotectin Testing Goes Mobile With advances in technology and the ubiquitous use of mobile devices, a huge opportunity has arisen to change the way some healthcare services are provided. This is especially applicable to the management of chronic conditions. With most people owning a mobile device or tablet this becomes a convenient way for patients to

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Diagnosing IBD

Faecal Calprotectin in Primary Care as a Decision Diagnostic for Inflammatory Bowel Disease and Irritable Bowel SyndromeNICE DG11 faecal calprotectin diagnostic tests for inflammatory diseases of the bowel proposed that faecal calprotectin should be used as part of the assessment of IBD and IBS (NICE, 2013). This consensus document has been developed by experts in
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Calprotectin in Primary Care – Dr James Turvill

Dr. James Turvill, Consultant Gastroenterologist at York Teaching Hospital NHS Foundation Trust was one of the experts speaking at Alpha Laboratories Digestive Diseases Day in November 2017 where he discussed the application of calprotectin testing in clinical care. Since 2008 Dr. Turvill has developed a research interest in the use of biomarkers to facilitate in the

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Faecal calprotectin—ready for prime time?

Introduction Calprotectin is a heterodimer of calcium-binding proteins which belongs to the S-100 protein family. It is released from neutrophils and monocytes during cellular activation (or death) at sites of active inflammation, and accounts for upto 60% of the cytosolic protein in the granules of these cells. It is a highly stable protein, resists enzymatic

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NICE Calprotectin!

Faecal calprotectin testing hit the news headlines late last year following publication of the NICE diagnostic guidelines: ‘Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel’ (DG11). Measurement of faecal calprotectin is considered to provide a reliable indicator of gastrointestinal (GI) tract inflammation and numerous studies show that, while faecal calprotectin concentrations are significantly

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Adoption project for Faecal Calprotectin Diagnostics Tests

In October 2013 NICE produced guidance (DG11) recommending the use of faecal calprotectin testing to help doctors distinguish between inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis, and non-inflammatory bowel diseases, such as irritable bowel syndrome. You can read more about the NICE guidelines here. The Health Technologies Adoption Programme (HTAP) are now

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About Calprotectin

Calprotectin is a protein biomarker that is present in the faeces when intestinal inflammation occurs. Faecal calprotectin testing is helping to improve patient care and save money for the NHS. It prevents the need for unnecessary endoscopy procedures on many patients by screening out those with Irritable Bowel Syndrome (IBS). The symptoms of functional disorders such
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