Calprotectin News


Launch of IBD Toolkit for GPs

The RCGP, in partnership with Crohn’s and Colitis UK, has launched an IBD toolkit for GPs and healthcare professionals. Clinical Champion for Inflammatory Bowel Disease, Dr Kevin Barrett,  developed the toolkit with the patient representative Rachel Fowler and the project’s steering group. He comments “Inflammatory Bowel Disease affects at least 1 in 250 of the

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Evaluating CE Marked Protocols for fCAL turbo

Expanded Range of Instruments with CE Marked Protocols for BÜHLMANN fCAL® turbo assay

BÜHLMANN application specialist Christina Gabris has recently visited the UK to validate some new instrument protocols for the fCAL turbo assay. Christina spent time in hospitals around Newcastle to optimise CE marked protocols for the Beckman AU5800 and AU680. The range of instruments with CE marked protocols for fCAL turbo has now been expanded to 28 including: Roche: cobas c501 & c502, cobas c701

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Assays to meet increasing faecal calprotectin tests

Meeting the Demands for Increasing Faecal Calprotectin Tests

Labs are receiving increasing faecal calprotectin tests requests since NICE published Diagnostic Guideline 11: ‘Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel’. This recommends faecal calprotectin as a first-line test for patients presenting with gastrointestinal (GI) symptoms indicative of IBS or IBD. Pam Bowe, team manager in the Department of Biochemistry at the Cumberland Infirmary, describes the evolution of her laboratory procedures to cope

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Studying Calprotectin False at Luton and Dunstable University Hospital

False Positive Faecal Calprotectin? Don’t Believe It

Read about the work at  Luton and Dunstable University Hospital, where Louise Asser and her colleagues have been using small bowel capsule endoscopy, to review patients with an increased calprotectin but normal colonoscopy, to investigate them for small bowel pathology and re-evaluate presumed false positive calprotectin results.

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85% of Respondents Prefer IBDoc®

IBDoc® Calprotectin Patient Self Testing Pilot Study The Poster presented at BSG 21-23 June 2016, by a team at King’s College Hospital NHS Foundation Trust, discusses a recent study among a cohort of Crohn’s and Ulcerative Colitis patients.

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So How DO You Collect that Awkward Sample?

Poo Collection Made Easy Collecting poo even gets into the daily news! A recent article in the Daily Mail addressed the tricky subject of how many patients find collecting faecal samples difficult and distasteful. Dr Cliodna McNulty, Head of the Primary Care Unit at Public Health England, explained why it’s so important.

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Shedding Light from Above: PillCam

Most things in this day and age are getting smaller: crisps, chocolate, computers and now endoscopes. Whilst the traditional endoscope is still used in most clinical investigations, a new kid on the block is now emerging. With a completely different, convenient and minimally invasive approach PillCam® could also provide more information than traditional endoscopy.

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Be Powerful in Purple on World IBD Day

Tuesday 19 May is World IBD Day. 300,000 people in the UK and millions more worldwide are living with Crohn’s Disease, Ulcerative Colitis and other types of IBD. Crohn’s and Colitis UK is asking people to wear purple (the international colour for IBD) on World IBD Day to help boost awareness about Crohn’s Disease and

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Ascites Calprotectin

Spontaneous bacterial peritonitis (SBP) is an acute bacterial infection of ascitic fluid. It primarily occurs in patients with advanced cirrhosis and, generally, no source of the infecting agent is easily identifiable.

Fever, abdominal pain, altered mental status, abdominal tenderness, or hypotension in cirrhosis cases indicates SBP. In addition, patients with ascites admitted to the hospital for other reasons should undergo paracentesis to look for evidence of SBP.

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Does NSAID use affect the Faecal Calprotectin Result?

In a word – yes!

Is this clinically significant? in another word, no!

Most non-steroidal anti-inflammatory drugs (NSAID) cause gastric damage in short-term volunteer studies, ranging from erythema to ulcers. Recent estimates suggest that gastrointestinal (GI) bleeding attributable to nonselective NSAID accounts for nearly 34% of all GI bleeding cases (mostly upper GI bleeding) in the US and may have resulted in over 32,000 hospitalisations per year during the last decade.

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