False Positive Faecal Calprotectin? Don’t Believe It

Read about the work at  Luton and Dunstable University Hospital, where Louise Asser and her colleagues have been using small bowel capsule endoscopy, to review patients with an increased calprotectin but normal colonoscopy, to investigate them for small bowel pathology and re-evaluate presumed false positive calprotectin results.

The Camera Never Lies

Causes of false positive calprotectin have been listed as infections, malignancy, drugs such as NSAID, food allergy, coeliac and cirrhosis. However, Crohn’s disease can affect any part of the GI tract and up to 30% of patients may have disease confined to the small bowel.

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