Freedom Through Diagnosis

Freedom Through Diagnosis

Reliable non-invasive differentiation between IBD and IBS. Faecal Calprotectin is an established protein biomarker that is helping to improve patient care and save money for the NHS.

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One Test or One Thousand

One Test or One Thousand

Alpha Laboratories offers the widest range of test formats for the measurement of human faecal Calprotectin in the UK. From single point of care tests to high throughput open access laboratory assays, you can trust our experience to help you find the best way for your testing regime and your patients.

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New: Calprotectin Self-Testing

New: Calprotectin Self-Testing

Alpha Laboratories has expanded the offering of BÜHLMANN Calprotectin tests with the launch of the IBDoc® which is the first CE marked Calprotectin home test. It enables more frequent monitoring for better management of IBD conditions.

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NICE Diagnostics Guidance [DG11]

NICE Diagnostics Guidance [DG11]

[DG11] Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel.
NICE recommends the use of faecal calprotectin as a first-line test in patients presenting with gastrointestinal symptoms indicative of IBS or IBD.

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What is Calprotectin?

Calprotectin is a protein biomarker that indicates the migration of neutrophils to the intestinal mucosa, occuring during inflammatory bowel disease (IBD). It is used to distinguish between IBD and non-inflammatory disorders and to monitor IBD disease activity. It helps improve patient care and reduce health care costs by screening out patients with Irritable Bowel Syndrome (IBS), thus preventing the need for unnecessary endoscopy procedures.

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Calprotectin Assays

Whether you want to perform the test within Primary Care, in the Gastroenterology Clinic or the Hospital Laboratory, or even empower your patients to test themselves, Alpha Laboratories offers the widest range of test formats for the measurement of Human Faecal Calprotectin in the UK.
From individual home kits up to high throughput automated analysis we can support your calprotectin testing needs.

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Benefits of  Calprotectin Tests

The NHS Centre for Evidence-based Purchasing concluded in 2010 that using calprotectin tests for differentiating between IBS and Inflammatory Bowel Disease (IBD) supports improvements in patient management and offers substantial cost savings.
Since 2013 NICE has recommended calprotectin tests to support clinicians with the differential diagnosis of IBD or irritable IBS in adults with recent onset lower gastrointestinal symptoms.

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Recent Calprotectin Resources


Dorset-County-Hospital
IBDoc®: Early Value in a District General Hospital Inflammatory Bowel Disease Service

At the European Crohn’s and Colitis Organisation, 13th Congress in Vienna in February

Digestive Diseases Day Calprotectin Survey results
View the Results of the Digestive Diseases Day Calprotectin Survey

On the 15th November 2017, Alpha Laboratories held a Digestive Diseases

Calprotectin in Primary Care – Dr James Turvill

Dr. James Turvill, Consultant Gastroenterologist at York Teaching Hospital NHS Foundation Trust

Mary OConnell
Bringing Calprotectin Testing In-house on the Abbott Architect C8000

Mary O’Connell née Deasy, Biochemistry Department Mercy University Hospital Cork, Ireland

Featured Products


  • BÜHLMANN fCAL® Calprotectin ELISA
  • Quantum Blue® fCAL Rapid Test
  • Ascites-Calprotectin-1Calprotectin in Ascites
  • Calprotectin Extraction
  • Calprotectin Sample Handling