Calprotectin-PublicationsYou’ll find a list of relevant calprotectin papers and posters relating to the efficacy of Calprotectin testing on this page.

General Calprotectin Papers

Schoepfer et al : Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis… Smith and Gaya: Utility of faecal calprotectin analysis in adult inflammatory bowel disease  Burri and Beglinger: The use of fecal calprotectin as a biomarker in gastrointestinal disease.   Waugh et al:  Faecal calprotectin testing for differentiating amongst inflammatory and non-inflammatory bowel diseases Naismith et al: A prospective evaluation of the predictive value of faecal calprotectin in quiescent Crohn’s disease 
Klinberg et al: A longitudinal study of fecal calprotectin and the development of inflammatory bowel disease in ankylosing spondylitis   El-Matary et al: Impact of Fecal Calprotectin Measurement on Decision-making in Children with Inflammatory Bowel Disease  
Turvill et al: Validation of a care pathway for the use of faecal calprotectin in monitoring patients with Crohn’s disease 
Davidson and Lock: Paediatric reference ranges for faecal calprotectin: a UK study T. Vogl et al. : Towards a Reference Material for the Standardization of Calprotectin (S100A8/A9; MRP8/14) Immunoassays
Moniuszko et al.: Rapid fecal calprotectin test for prediction of mucosal inflammation in ulcerative colitis and Crohn disease
Read the NICE Medtech innovation briefing [MIB132] on Point-of-care and home faecal calprotectin tests 
Read the BIVDA/Innovate UK Report –  Three simple tests could save the NHS at least £6.9 billion 

Calprotectin in Primary Care

Turvill et al.: Evaluation of a faecal calprotectin care pathway for use in primary care
Pavlidis et al.: Diagnostic accuracy and clinical application of faecal calprotectin in adult patients presenting with gastrointestinal symptoms in primary care 
Kok et al.: Diagnostic accuracy of point-of-care fecal calprotectin…… 

Calprotectin and Mucosal Healing

Yamamoto et al. De Vos et al De Vos et al

Faecal Calprotectin in Patients with Suspected Colorectal Cancer

Turvill et al. 2016

Correlation between Quantum Blue® and Calprotectin ELISA (EK-CAL)

The laboratory shall have a mechanism for ensuring that examinations performed using different procedures or equipment or at different sites give comparable results, in particular, throughout clinically appropriate intervals

CPA F.3.5

Related reading:

Sydora et al Lobaton et al  Hessels et al  Coorevits et al Ortega et al


Linearity of BÜHLMANN Calprotectin range

Eurofins Poster


Stability of samples and extracts

Eurofins Poster


Determination of cut-off value

Manz Paper   Walsh A. et al. ECCO P262


Clinical Correlation of BÜHLMANN Calprotectin range

Manz Paper


Quantum Blue Publications

Sydora et al : Validation of a point-of-care desk top device to quantitate fecal calprotectin…
 Lobaton et al: A new rapid test for fecal calprotectin predicts endoscopic remission and postoperative recurrence in Crohn’s disease   Hessels et al: Evaluation of Prevent ID and Quantum Blue rapid tests for fecal calprotectin    Coorevits et al: Faecal calprotectin: comparative study of the Quantum Blue rapid test and an established ELISA method.   Wassell: Evaluation of the Quantum Blue® rapid test for faecal calprotectin. Ortega et al:A New Rapid Quantitative Test for Fecal Calprotectin Predicts Endoscopic Activity in Ulcerative Colitis   Dhanda et al: Faecal Calprotectin is a Cost-Effective Method of Assessing Activity of Inflammatory Bowel Disease 
Ortega et al: Crohn’s Disease Ortega et al:  Ulcerative Colitis Quantum Blue Literature List 2013

BÜHLMANN Calprotectin ELISA Publications

Eurofins Poster: Method validation for the quantification of fecal Calprotectin.   Coorevits et al: Faecal calprotectin: comparative study of the Quantum Blue rapid test and an established ELISA method.    Manz: Value of fecal calprotectin in the evaluation of patients with abdominal discomfort: an observational study   Naismith: A prospective single-centre evaluation of the intra-individual variability of faecal calprotectin in quiescent Crohn’s disease Burri et al:  Monoclonal antibody testing for fecal calprotectin is superior to polyclonal testing…

BÜHLMANN fCAL® turbo Publications

fCAL turbo Datasheet   Analytical Performance of fCAL turbo (Poster)   Total Automation of Calprotectin Measurement in Faeces (Poster)
De Sloovere et al:  Analytical and diagnostic performance of two automated fecal calprotectin immunoassays…
BÜHLMANN fCAL® turbo:  Faecal Calprotectin Assay Proves Consistent between Multiple Analysers
Bowe et al:  Evaluation of the BÜHLMANN fCAL™ turbo Calprotectin Method on the Roche Cobas 6000 (c501)  
Evans et al:  Verification and implementation of faecal calprotectin using the BÜHLMANN fCAL® turbo assay (Abbott ARCHITECT) 
O’Connell M: Evaluation of the BÜHLMANN fCAL Turbo Faecal Calprotectin Assay on the Abbott Architect C8000.
Comparison to the Phadia EliA and the IBDoc® home test kit.

O’Connell M – Poster: BÜHLMANN fCAL® turbo Faecal Calprotectin Assay on Abbott Architect C8000

BÜHLMANN IBDoc Publications

Beyer et al: Usability Study of a Smartphone-Based Calprotectin Home Test
Reinhard et al: Usability study of a smartphone-based patient monitoring system measuring Calprotectin for therapy follow-up
Weber et al: Validation of a smartphone-based patient monitoring system measuring calprotectin as the therapy follow-up marker
Parr et al: Home-testing of faecal calprotectin using the IBDoc™ system: a comparative pilot study
Raker et al: Home testing for faecal calprotectin: follow-up results from the first UK trial
Ungar et al: Home smart-phone based measurement of fecal calprotectin by IBD patients:
correlation with laboratory assay and applicability as patient-friendly monitoring tool

Heida et al: Home vs Hospital-based Analysis of stool calprotectin comparison of two monitoring methods
Bello et al: Usability of a home-based test for the measurement of fecal calprotectin in IBD patients
Heida et al: Agreement Between Home-Based Measurement of Stool Calprotectin and ELISA Results for Monitoring Inflammatory Bowel Disease Activity
Elsafi et al: Cost effective of IBDoc as a surrogate marker of mucosal healing in IBD patients post induction of biological agents Avery and Wilson: IBDoc® Self-care/Point of care Calprotectin Test: Early Value in a District General Hospital Inflammatory Bowel Disease Service
Gastroenterology Today Spring 2018: Big Changes Coming Soon to a Clinic Near You – Calprotectin Testing Goes Mobile


NHS Centre for Evidence-based Purchasing Reviews

Calprotectin Evidence Review Calprotectin Economic Review

NHS Technology Adoption Centre

 Faecal Calprotectin testing in Primary Care Report

Serum Calprotectin

Bojko: Measurement of blood calprotectin (MRP-8/MRP-14) levels in patients with juvenile idiopathic arthritis