Calprotectin for Laboratories


Quantum Blue and ELISA Correlation
Quantum Blue and ELISA Correlation

Alpha Laboratories offers a number of test formats for the measurement of human faecal Calprotectin for laboratories in the UK.

We also further support you with a comprehensive range of compatible collection and sample handling products.

Choose from either:

  • BÜHLMANN IBDoc® Calprotectin Patient Self  (Home) Test
  • BÜHLMANN Quantum Blue® for lower test throughput or Point-of-Care
  • BÜHLMANN fCAL® ELISA for high throughput and automation
  • BÜHLMANN fCAL® turbo for high throughput testing on standard clinical chemistry analysers

You can see on the right the graph showing the correlation between methods.

BÜHLMANN Quantum Blue® Calprotectin

Quantum Blue Calprotectin Reader for Laboratories

Quantum Blue is a rapid, quantitative Calprotectin testing platform for point-of-care or lower throughput requirements.

If your Calprotectin test request number is too low to achieve a reasonable turn around time using an ELISA method, Quantum Blue® provides a comprehensive, low cost, entry-level Calprotectin testing platform. Quantum Blue can be used in either the clinic or laboratory setting.

  • Individually sealed tests
  • Based on established lateral flow technology
  • Provides a quantitative measure of Calprotectin in faecal samples but in a rapid  test format
  • Quantitative result in 12 mins
  • Results can be downloaded to the LIS
  • Simple and rapid extraction and test process
  • Compact bench-top reader
  • Excellent correlation with the Bühlmann Calprotectin ELISA: uses a consistent cut off value (50µg/g)
  • Measurable range 30-300µg/g, 100-1800µg/g or 30-1000µg/g Calprotectin in stool samples

Read more about Quantum Blue Buy Quantum Blue online


EK-CAL Calprotectin ELISA
fCAL Calprotectin ELISA

The Calprotectin ELISA from BÜHLMANN can be easily automated on many commercially available ELISA processor. There is CE marked protocols available for the Dynex DS2 and DSx as well as protocols available for the Triturus. Alpha Laboratories Ltd also supply the Dynex DS2 for capital purchase or reagent rental.

All reagents, standards and controls are provided in one kit and are ready for use. There is no requirement for reconstituting any component, apart from the wash buffer. This minimizes any errors as well as ensuring a long shelf life.

Two different protocols are available in one kit in order to ensure that the range for IBD and IBS differentiation and therapy monitoring is covered. The ranges are 10-600µg/g or 30-1800µg/g. A consistent cut-off of 50µg/g is used through out the Bühlmann Calprotectin range.

A simple extraction procedure for Calprotectin is available using either the CALEX Cap, Schebo or Roche extraction devices. See below (link to extraction devices)

Read more about the Calprotectin ELISA Buy the Calprotectin ELISA online


fCAL turbo calprotectin turbidimetric assay
fCAL turbo Calprotectin Turbidimetric Assay

Speed, Quality and Flexibility in Calprotectin Quantification

BÜHLMANN fCAL® turbo is a flexible turbidimetric assay for faecal calprotectin applicable on many major clinical chemistry platforms.

The new BÜHLMANN fCAL® turbo is a turbidimetric immunoassay based on the standardization of the BÜHLMANN fCAL® ELISA, which is globally established in laboratories as the gold standard for calprotectin measurements.