NICE Calprotectin!

Faecal calprotectin testing hit the news headlines late last year following publication of the NICE diagnostic guidelines: ‘Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel’ (DG11). Measurement of faecal calprotectin is considered to provide a reliable indicator of gastrointestinal (GI) tract inflammation and numerous studies show that, while faecal calprotectin concentrations are significantly…

Adoption project for Faecal Calprotectin Diagnostics Tests

In October 2013 NICE produced guidance (DG11) recommending the use of faecal calprotectin testing to help doctors distinguish between inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis, and non-inflammatory bowel diseases, such as irritable bowel syndrome. You can read more about the NICE guidelines here. The Health Technologies Adoption Programme (HTAP) are now…

Calprotectin and Mucosal Healing

Calprotectin and Mucosal Healing

Traditionally, the treatment aim in patients with Inflammatory Bowel Disease (IBD) has been clinical remission evaluated by clinical indices, especially among patients with symptoms of predominantly inflammatory origin1. However, the correlation between such indices and the degree of inflammation has been questioned and Saverymuttu et al2 showed low correlation between the Crohn Disease Activity Index…